Pharmacology TB Drugs #1

Question

Which teaching is correct for the nurse to teach a client taking isoniazid (INH) for a recent diagnosis of tuberculosis?

Answers

  1. Explain the medication should be taken at least 2-4 weeks
    • Rationale:

      This answer is not correct because INH is only effective if taken for 6-12 months. Taking the medication only 2-4 weeks would not be effective treatment for tuberculosis.

  2. Teach the importance of reporting tingling in the feet
    • Rationale:

      This answer is correct because INH has the side effect of peripheral neuropathy. Signs and symptoms of this include tingling, numbness, and difficulty walking. The client should be taught these clinical manifestations and to report these to the healthcare provider as soon as possible.

  3. Tell the client to have kidney function evaluated weekly
    • Rationale:

      This answer is not correct because liver function, not kidney function, needs to be assessed in the client taking INH. These labs would include AST/ALT. The careful monitoring is due to the toxicity INH has on the liver.

  4. Inform the client to not wear soft contact lenses during treatment
    • Rationale:

      This answer is not correct because rifampin, not INH, discolors body fluid, such as tears. With rifampin, not INH, the client should be encouraged to wear their glasses instead of soft contact lenses so the red discoloration in tears does not stain the contact lenses.

Overview

Isoniazid (INH) is used to treat and prevent tuberculosis. There are many important things to teach the client, including the importance of reporting signs and symptoms of peripheral neuropathy.

Explanation

Learning Outcomes

Isoniazid (INH) is an antibiotic used to treat and prevent tuberculosis (TB). The medication has several side effects, including peripheral neuropathy. Signs and symptoms of this include tingling, numbness, and difficulty walking. The client should be taught these clinical manifestations and to report these to the healthcare provider as soon as possible. Additional client teaching for this medication includes taking the complete prescribed dose for the prescribed time (6-12 months), the importance of taking B6 (pyridoxine) due to the risk of deficiency and subsequent peripheral neuropathy, and the importance of returning for periodic liver function tests (AST and ALT) due to the toxicity to the liver.

Test Taking Tip

Unique things about certain drugs should be focused on when studying medications, such as the normal finding of red-discoloration that occurs with body fluids with use of rifampin. Client teaching is very important when common, benign findings appear to look like blood.

Video Rationale