Pharmacology Antibiotics #7

Question

A client in the medical surgical unit receives infusion of vancomycin twice daily and will require a trough level prior to the next dose. When should the nurse ensure collection of the blood sample for the trough level?

Answers

  1. 1 hour after the next dose is administered.
    • This answer is not correct because blood for a trough level is drawn just before the client’s next vancomycin dose, not 1 hour after the dose. Peak blood levels are drawn 1 to 2 hours after the vancomycin dose is complete..

  2. 1-2 hours before the next dose is administered.
    • This answer is not correct because blood for a trough level is drawn just before the client’s next vancomycin dose, not 1-2 hours before the next dose. Peak blood levels are drawn 1 to 2 hours after the vancomycin dose is complete.

  3. Immediately before administering the next dose.
    • This answer is correct because blood for a trough level is drawn just before the client’s next vancomycin dose. Peak blood levels are drawn 1 to 2 hours after the vancomycin dose is complete. Peak and trough levels are drawn for vancomycin to make sure the client is receiving enough medication to fight the infection, but not too much of medication to cause toxicity symptoms.

  4. Immediately after administering the next dose.
    • This answer is not correct because blood for a trough level is drawn just before the client’s next vancomycin dose, not immediately after administering the next dose. Peak blood levels are drawn 1 to 2 hours after the vancomycin dose is complete.

Overview

Vancomycin requires a trough level to be drawn immediately before administration of the next dose.

Learning Outcomes

Vancomycin is a glycopeptide antibiotic. There are many side effects with this medication, including nephrotoxicity. Peak and trough levels are drawn for vancomycin to make sure the client is receiving enough medication to fight the infection, but not too much of medication to cause toxicity symptoms. Trough blood levels are drawn just before the client’s next vancomycin dose. Peak blood levels are drawn 1 to 2 hours after the vancomycin dose is complete.

Test Taking Tip

When trying to remember important points about vancomycin, remember “red van” for red-man syndrome and the when making a “V” on vancomycin you go down (trough) and as you come back up to finish the “V” for the peak.