Pharmacology Miscellaneous Neurological Condition Drugs #1

Question

A client with Parkinson’s disease (PD) was prescribed carbidopa and levodopa a few months ago. How does the nurse evaluate if the medication is therapeutically effective in the client?

Answers

  1. 1. The client has increased urinary output
    • Rationale:

      This answer is not correct because increased urinary output is a side effect nor a goal of therapy of carbidopa and levodopa. Dizziness, dry mouth, and constipation are common side effects of carbidopa and levodopa.

  2. 2. The client has increased diarrhea
    • Rationale:

      This answer is not correct because diarrhea is not the therapeutic goal of carbidopa-levodopa. Constipation, not diarrhea, is a side effect of carbidopa-levodopa.

  3. 3. The client has increased shuffling
    • Rationale:

      This answer is not correct because the goal of carbidopa-levodopa includes improvement of gait disturbances associated with Parkinson’s disease. A shuffling gait is a common symptom associated with PD.

  4. 4. The client has decreased tremors at rest
    • Rationale:

      This answer is correct because Parkinson’s disease is caused by lower quantities of dopamine in parts of the brain. Carbidopa and levodopa convert to dopamine after crossing the blood-brain barrier and helps balance acetylcholine and dopamine, thus helping to control Parkinson’s disease. Symptoms of Parkinson’s disease are progressive and include tremors at rest, unsteady gait, and weakness.

Overview

Carbidopa-levodopa is a commonly prescribed medication for Parkinson’s disease. The goal of treatment is treatment of symptoms associated with Parkinson’s disease.

Explanation

Learning Outcomes

Carbidopa-levodopa is a dopamine precursor used to treat symptoms of Parkinson’s disease. Parkinson’s disease symptoms occur due to decreasing levels of dopamine in the body. Symptoms of Parkinson’s disease are progressive and include tremors at rest, unsteady gait, and weakness.

Test Taking Tip

Watch for distractors in a question that address common symptoms of a disease rather than side effects or therapeutic goals of a medication.

Video Rationale