Patho Patho #7

Question

When only one copy of a mutated gene is required in order to display a disease, this is considered a(n):

Answers

  1. Autosomal dominant disorder
    • Rationale:

      This answer is correct because autosomal dominant disorders only require one copy of a mutated gene in order for a client to display characteristics of a disorder.

  2. Autosomal recessive disorder
    • Rationale:

      This answer choice is not correct as autosomal recessive disorders require two copies of the mutated gene for the client to display characteristics of the disorder.

  3. x-Linked disorder
    • Rationale:

      This answer choice is not correct because x-Linked disorders are disorders that affect sex chromosomes. Autosomal inherited disorders affect the non-sex chromosomes.

  4. Chromosomal disorder
    • Rationale:

      This answer choice is not correct because chromosomal disorders occur when there is an extra chromosome present or a chromosome deleted. There is not mutation, but rather an extra chromosome or a deleted chromosome with these types of disorders.

Overview

An autosomal dominant disorder is one in which the mutated gene is located on one of the non-sex chromosomes. Only one copy of the mutated gene is necessary in order to display characteristics of the disorder with an autosomal dominant pattern of inheritance.

Explanation

Learning Outcomes

With autosomal dominant patterns of inheritance, only one copy of a mutated gene is necessary in order for the client to display characteristics of a disease. Examples of autosomal dominant disorders include Huntingdon Disease and Marfan Syndrome. Autosomal gene mutations occur on one of the 22 pairs of autosomes, or nonsex chromosomes.

Test Taking Tip

Genetic patterns of inheritance are best learned by using a punnet square method. However, a basic understanding of the 4 basic categories of genetic disorders (autosomal dominant/ recessive, sex linked and chromosomal) is essential in order to master this content.

Video Rationale