Patho Patho #20

Question

The nurse recognizes which as the most serious potential complication associated with Trisomy 21?

Answers

  1. Congenital heart defects
    • Rationale:

      This answer is correct because congenital heart defects are the most common cause of mortality in clients with trisomy 21 and are therefore the most critical potential complication of the disorder.

  2. Cognitive deficiencies
    • Rationale:

      This answer choice is not correct because, although trisomy 21 causes intellectual disability, this is not the most critical potential complication of the disorder.

  3. Aortic aneurysms
    • Rationale:

      This answer choice is not correct because aortic aneurysms are not typically associated with trisomy 21. Chronic, long-standing hypertension is the most common etiology of aortic aneurysms.

  4. Abnormal facial features
    • Rationale:

      This answer choice is not correct because although trisomy 21 is associated with facial abnormalities, congenital heart defects are the most critical potential complication associated with the disorder.

Overview

Trisomy 21 is a genetic disorder caused by the presence of a third copy of chromosome 21. It is usually associated with delays in growth, intellectual disability, and certain characteristic facial features. However, the most critical potential complication of Trisomy 21 are congenital heart defects often leading to heart failure in these clients.

Explanation

Learning Outcomes

Trisomy 21 is also known as Down Syndrome in which there is a third copy of chromosome 21. The focus of this question is asking the nurse to determine the most critical potential complication of this genetic disorder. Congenital heart defects are prevalent in clients with Trisomy 21which may lead to heart failure and death in clients with the disorder.

Test Taking Tip

Always apply A-B-C. Congenital heart defects lead to heart failure which affects circulation. This makes congenital heart defects the most critical and potentially deadly complication of trisomy 21.

Video Rationale