Endocrine Question #41


The nurse is providing instructions to a client with new diagnosis of Graves’ Disease who will also receive the prescription for methimazole (Tapazole). What instruction will the nurse provide? (Select all that apply)


  1. Take solu-cortef with methimazole daily to reduce adverse effects.
    • Rationale:
  2. Take methimazole at the same time each day.
    • Rationale:
  3. Follow-up with the clinic for a complete blood count in 4 weeks.
    • Rationale:
  4. Follow-up with the clinic for laboratory blood test for T3
    • Rationale:



Methimazole is a treatment for Graves’ Disease caused and hyperthyroidism and should be taken daily at the same time. It should not be taken with steroids. Lab tests for CBC should be periodically monitored for agranulocytosis. Thyroid studies should be monthly during initial therapy and every 2-3 months afterwards.

Learning Outcomes

Test Taking Tip

Video Rationale