Endocrine Question #17
The nurse is caring for a client with hypothyroidism who receives levothyroxin daily and is scheduled for a procedure under sedation. The nurse contacts the health provider because of risk of adverse effects when administering which of the ordered medication?
- Benzodiazepine pre-medication
- Proton pump inhibitor pre-medication
- Benadryl pre-medication
- Reglan pre-medication
Benzodiazepines and hypnotic and may increase sedation and respiratory depression when taken with levothyroxine. Levothyroxine has a half-life of 6-7 days and peak in 1-3 weeks with duration of 1-3 weeks, so any procedure requiring sedation should require notification of anesthesia provider and health provider. Proton pump inhibitors, benadryl, and reglan do not pose severe reactions with levothyroxine.