Cardiac Question #41


The nurse is caring for a client who is prescribed hydrochlorothiazide for hypertension. Following administration of this medication, the nurse should anticipate what effect?


  1. Increased blood pressure related to increased cardiac output
    • Rationale:
  2. Increased urine output related to diuretic effect
    • Rationale:
  3. Elevated potassium
    • Rationale:
  4. Mild agitation
    • Rationale:



Hydrochorothiazide is prescribed for management of mild to moderate hypertension and edema. Therapeutic effects occur with lowering of blood pressure and diuresis for mobilization of fluid volume. Therefore, increased urine output related to the diuretic effect will occur. The drug may cause a decrease in potassium, not an increase (as in spironolactone, a potassium sparing diuretic). Mild agitation is not a common adverse reaction.

Learning Outcomes

Test Taking Tip

Video Rationale